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Genome-Wide DNA Methylation and Hydroxymethylation Changes Revealed Epigenetic Regulation of Neuromodulation and Myelination in Yak Hypothalamus
Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC and 5hmC in brain regions of animals under natural high-altitude conditions. We used oxidative reduce...
Autores principales: | Chai, Zhixin, Wu, Zhijuan, Ji, Qiumei, Wang, Jikun, Wang, Jiabo, Wang, Hui, Zhang, Chengfu, Zhong, Jincheng, Xin, Jinwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503545/ https://www.ncbi.nlm.nih.gov/pubmed/34646294 http://dx.doi.org/10.3389/fgene.2021.592135 |
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