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Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients

BACKGROUND: Solid organ transplant (SOT) patients have increased risk of complications, infection, and mortality after elective total hip arthroplasty (THA). The study aims to compare SOT recipients' clinical outcomes to a matched group of nontransplant patients after nonelective THA and hemiar...

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Autores principales: Ledford, Cameron K., VanWagner, Michael J., Spaulding, Aaron C., Spencer-Gardner, Luke S., Wilke, Benjamin K., Porter, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503575/
https://www.ncbi.nlm.nih.gov/pubmed/34660866
http://dx.doi.org/10.1016/j.artd.2021.09.006
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author Ledford, Cameron K.
VanWagner, Michael J.
Spaulding, Aaron C.
Spencer-Gardner, Luke S.
Wilke, Benjamin K.
Porter, Steven B.
author_facet Ledford, Cameron K.
VanWagner, Michael J.
Spaulding, Aaron C.
Spencer-Gardner, Luke S.
Wilke, Benjamin K.
Porter, Steven B.
author_sort Ledford, Cameron K.
collection PubMed
description BACKGROUND: Solid organ transplant (SOT) patients have increased risk of complications, infection, and mortality after elective total hip arthroplasty (THA). The study aims to compare SOT recipients' clinical outcomes to a matched group of nontransplant patients after nonelective THA and hemiarthroplasty for acute femoral neck fracture (FNF). METHODS: A retrospective review identified 31 SOT patients undergoing hip arthroplasty (24 hemiarthroplasty and 7 THA) for FNF and were matched 1:1 to non-SOT patients based on age, sex, body mass index, surgical procedure, and year of surgery. Patient survivorship, perioperative outcomes, complications, and reoperations were compared. The mean follow-up was 3 years. RESULTS: The estimated survivorship free from mortality for SOT and non-SOT patients at 1- year was not different (77% and 84%, respectively, P = .52). The 90-day readmission rate was significantly higher with 8 (26%) in the SOT cohort and none in the non-SOT group (P < .01). Major medical complications occurred in 16% of SOT patients compared to 5% in controls (P = .21). Three (10%) reoperations/revisions were required for SOT patients and none in non-SOT group (P = .24). CONCLUSION: SOT recipients undergoing nonelective hip arthroplasty for FNF demonstrated increased readmission rates compared to matched controls. For this rare clinical scenario, diligent perioperative care by surgeons and multidisciplinary transplant specialists is necessary to mitigate increased risk of SOT patients.
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spelling pubmed-85035752021-10-15 Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients Ledford, Cameron K. VanWagner, Michael J. Spaulding, Aaron C. Spencer-Gardner, Luke S. Wilke, Benjamin K. Porter, Steven B. Arthroplast Today Original Research BACKGROUND: Solid organ transplant (SOT) patients have increased risk of complications, infection, and mortality after elective total hip arthroplasty (THA). The study aims to compare SOT recipients' clinical outcomes to a matched group of nontransplant patients after nonelective THA and hemiarthroplasty for acute femoral neck fracture (FNF). METHODS: A retrospective review identified 31 SOT patients undergoing hip arthroplasty (24 hemiarthroplasty and 7 THA) for FNF and were matched 1:1 to non-SOT patients based on age, sex, body mass index, surgical procedure, and year of surgery. Patient survivorship, perioperative outcomes, complications, and reoperations were compared. The mean follow-up was 3 years. RESULTS: The estimated survivorship free from mortality for SOT and non-SOT patients at 1- year was not different (77% and 84%, respectively, P = .52). The 90-day readmission rate was significantly higher with 8 (26%) in the SOT cohort and none in the non-SOT group (P < .01). Major medical complications occurred in 16% of SOT patients compared to 5% in controls (P = .21). Three (10%) reoperations/revisions were required for SOT patients and none in non-SOT group (P = .24). CONCLUSION: SOT recipients undergoing nonelective hip arthroplasty for FNF demonstrated increased readmission rates compared to matched controls. For this rare clinical scenario, diligent perioperative care by surgeons and multidisciplinary transplant specialists is necessary to mitigate increased risk of SOT patients. Elsevier 2021-10-06 /pmc/articles/PMC8503575/ /pubmed/34660866 http://dx.doi.org/10.1016/j.artd.2021.09.006 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Ledford, Cameron K.
VanWagner, Michael J.
Spaulding, Aaron C.
Spencer-Gardner, Luke S.
Wilke, Benjamin K.
Porter, Steven B.
Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title_full Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title_fullStr Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title_full_unstemmed Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title_short Outcomes of Femoral Neck Fracture Treated With Hip Arthroplasty in Solid Organ Transplant Patients
title_sort outcomes of femoral neck fracture treated with hip arthroplasty in solid organ transplant patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503575/
https://www.ncbi.nlm.nih.gov/pubmed/34660866
http://dx.doi.org/10.1016/j.artd.2021.09.006
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