Cargando…
Dose-dependent effects of pharmaceutical treatments on bone matrix properties in ovariectomized rats
As both anabolic and anti-catabolic osteoporosis drugs affect bone formation and resorption processes, they may contribute to bone's overall mechanical behavior by altering the quality of the bone matrix. We used an ovariectomized rat model and a novel fracture mechanics approach to investigate...
Autores principales: | Karim, Lamya, Kwaczala, Andrea, Vashishth, Deepak, Judex, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503587/ https://www.ncbi.nlm.nih.gov/pubmed/34660852 http://dx.doi.org/10.1016/j.bonr.2021.101137 |
Ejemplares similares
-
Heterogeneous Glycation of Cancellous Bone and Its Association with Bone Quality and Fragility
por: Karim, Lamya, et al.
Publicado: (2012) -
Physicochemical Position-Dependent Properties in the Protein Secondary Structures
por: Saghapour, Ehsan, et al.
Publicado: (2019) -
Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
por: Jackson, Erica, et al.
Publicado: (2021) -
Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner
por: Meakin, Lee B, et al.
Publicado: (2017) -
3D-Printed PCL/Zn scaffolds for bone regeneration with a dose-dependent effect on osteogenesis and osteoclastogenesis
por: Wang, Siyi, et al.
Publicado: (2022)