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Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis

Polyamines are fundamental molecules of life, and their deep evolutionary history is reflected in extensive biosynthetic diversification. The polyamines putrescine, agmatine, and cadaverine are produced by pyridoxal 5′-phosphate-dependent L-ornithine, L-arginine, and L-lysine decarboxylases (ODC, AD...

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Detalles Bibliográficos
Autores principales: Li, Bin, Liang, Jue, Hanfrey, Colin C., Phillips, Margaret A., Michael, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503589/
https://www.ncbi.nlm.nih.gov/pubmed/34560100
http://dx.doi.org/10.1016/j.jbc.2021.101219