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Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation

The mitochondrial matrix protease LONP1 is an essential part of the organellar protein quality control system. LONP1 has been shown to be involved in respiration control and apoptosis. Furthermore, a reduction in LONP1 level correlates with aging. Up to now, the effects of a LONP1 defect were mostly...

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Detalles Bibliográficos
Autores principales: Pollecker, Karen, Sylvester, Marc, Voos, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503632/
https://www.ncbi.nlm.nih.gov/pubmed/34461102
http://dx.doi.org/10.1016/j.jbc.2021.101134