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Ursolic Acid Targets Glucosyltransferase and Inhibits Its Activity to Prevent Streptococcus mutans Biofilm Formation

Streptococcus mutans (S. mutans), the prime pathogen of dental caries, can secrete glucosyltransferases (GTFs) to synthesize extracellular polysaccharides (EPSs), which are the virulence determinants of cariogenic biofilms. Ursolic acid, a type of pentacyclic triterpene natural compound, has shown p...

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Detalles Bibliográficos
Autores principales:	Liu, Yucui, Huang, Yanxin, Fan, Cong, Chi, Zhongmei, Bai, Miao, Sun, Luguo, Yang, Li, Yu, Chunlei, Song, Zhenbo, Yang, Xiaoguang, Yi, Jingwen, Wang, Shuyue, Liu, Lei, Wang, Guannan, Zheng, Lihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503646/ https://www.ncbi.nlm.nih.gov/pubmed/34646258 http://dx.doi.org/10.3389/fmicb.2021.743305

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