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Preliminary Evidence for IL-10-Induced ACE2 mRNA Expression in Lung-Derived and Endothelial Cells: Implications for SARS-Cov-2 ARDS Pathogenesis

Angiotensin-converting enzyme 2 (ACE2) is a receptor for the spike protein of SARS-COV-2 that allows viral binding and entry and is expressed on the surface of several pulmonary and non-pulmonary cell types, with induction of a “cytokine storm” upon binding. Other cell types present the receptor and...

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Detalles Bibliográficos
Autores principales:	Albini, Adriana, Calabrone, Luana, Carlini, Valentina, Benedetto, Nadia, Lombardo, Michele, Bruno, Antonino, Noonan, Douglas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503675/ https://www.ncbi.nlm.nih.gov/pubmed/34646263 http://dx.doi.org/10.3389/fimmu.2021.718136

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