Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints

Allergic diseases are immune-mediated diseases. Allergies share a common immunopathogenesis, with specific differences according to the specific disease. Mesenchymal stem/stromal cells (MSCs) have been applied to people suffering from allergic and many other diseases. In this review, the immunologic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun-Young, Kim, Hyuk Soon, Hong, Ki-Sung, Chung, Hyung-Min, Park, Se-Pill, Noh, Geunwoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503727/
https://www.ncbi.nlm.nih.gov/pubmed/34635172
http://dx.doi.org/10.1186/s13287-021-02583-4
_version_ 1784581191221903360
author Kim, Eun-Young
Kim, Hyuk Soon
Hong, Ki-Sung
Chung, Hyung-Min
Park, Se-Pill
Noh, Geunwoong
author_facet Kim, Eun-Young
Kim, Hyuk Soon
Hong, Ki-Sung
Chung, Hyung-Min
Park, Se-Pill
Noh, Geunwoong
author_sort Kim, Eun-Young
collection PubMed
description Allergic diseases are immune-mediated diseases. Allergies share a common immunopathogenesis, with specific differences according to the specific disease. Mesenchymal stem/stromal cells (MSCs) have been applied to people suffering from allergic and many other diseases. In this review, the immunologic roles of MSCs are systemically reviewed according to disease immunopathogenesis from a clinical viewpoint. MSCs seem to be a promising therapeutic modality not only as symptomatic treatments but also as causative and even preventive treatments for allergic diseases, including atopic dermatitis and chronic urticaria.
format Online
Article
Text
id pubmed-8503727
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-85037272021-10-12 Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints Kim, Eun-Young Kim, Hyuk Soon Hong, Ki-Sung Chung, Hyung-Min Park, Se-Pill Noh, Geunwoong Stem Cell Res Ther Review Allergic diseases are immune-mediated diseases. Allergies share a common immunopathogenesis, with specific differences according to the specific disease. Mesenchymal stem/stromal cells (MSCs) have been applied to people suffering from allergic and many other diseases. In this review, the immunologic roles of MSCs are systemically reviewed according to disease immunopathogenesis from a clinical viewpoint. MSCs seem to be a promising therapeutic modality not only as symptomatic treatments but also as causative and even preventive treatments for allergic diseases, including atopic dermatitis and chronic urticaria. BioMed Central 2021-10-11 /pmc/articles/PMC8503727/ /pubmed/34635172 http://dx.doi.org/10.1186/s13287-021-02583-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Kim, Eun-Young
Kim, Hyuk Soon
Hong, Ki-Sung
Chung, Hyung-Min
Park, Se-Pill
Noh, Geunwoong
Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title_full Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title_fullStr Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title_full_unstemmed Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title_short Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
title_sort mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503727/
https://www.ncbi.nlm.nih.gov/pubmed/34635172
http://dx.doi.org/10.1186/s13287-021-02583-4
work_keys_str_mv AT kimeunyoung mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints
AT kimhyuksoon mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints
AT hongkisung mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints
AT chunghyungmin mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints
AT parksepill mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints
AT nohgeunwoong mesenchymalstemstromalcelltherapyinatopicdermatitisandchronicurticariaimmunologicalandclinicalviewpoints

Ejemplares similares