Molecular docking analysis of human JAK2 with compounds from tomatoes

Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) wi...

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Detalles Bibliográficos
Autores principales: Rekha, Umapathy Vidhya, Anita, M, Bhuminathan, S, Sadhana, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503773/
https://www.ncbi.nlm.nih.gov/pubmed/34675459
http://dx.doi.org/10.6026/97320630016742
Descripción
Sumario:Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration.

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