Molecular docking analysis of human JAK2 with compounds from tomatoes

Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) wi...

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Detalles Bibliográficos
Autores principales: Rekha, Umapathy Vidhya, Anita, M, Bhuminathan, S, Sadhana, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503773/
https://www.ncbi.nlm.nih.gov/pubmed/34675459
http://dx.doi.org/10.6026/97320630016742
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author Rekha, Umapathy Vidhya
Anita, M
Bhuminathan, S
Sadhana, K
author_facet Rekha, Umapathy Vidhya
Anita, M
Bhuminathan, S
Sadhana, K
author_sort Rekha, Umapathy Vidhya
collection PubMed
description Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration.
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spelling pubmed-85037732021-10-20 Molecular docking analysis of human JAK2 with compounds from tomatoes Rekha, Umapathy Vidhya Anita, M Bhuminathan, S Sadhana, K Bioinformation Research Article Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration. Biomedical Informatics 2020-10-31 /pmc/articles/PMC8503773/ /pubmed/34675459 http://dx.doi.org/10.6026/97320630016742 Text en © 2020 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Rekha, Umapathy Vidhya
Anita, M
Bhuminathan, S
Sadhana, K
Molecular docking analysis of human JAK2 with compounds from tomatoes
title Molecular docking analysis of human JAK2 with compounds from tomatoes
title_full Molecular docking analysis of human JAK2 with compounds from tomatoes
title_fullStr Molecular docking analysis of human JAK2 with compounds from tomatoes
title_full_unstemmed Molecular docking analysis of human JAK2 with compounds from tomatoes
title_short Molecular docking analysis of human JAK2 with compounds from tomatoes
title_sort molecular docking analysis of human jak2 with compounds from tomatoes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503773/
https://www.ncbi.nlm.nih.gov/pubmed/34675459
http://dx.doi.org/10.6026/97320630016742
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