Molecular docking analysis of COX-2 for potential inhibitors

Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further...

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Detalles Bibliográficos
Autores principales: Selvaraj, Jayaraman, Vishnupriya, Veeraraghavan, Sardar, Hussain, Balakrishna, Janardhana Papayya, Rex, Josephine, Mohan, Surapaneni Krishna, Vijayalakshmi, Periyasamy, Ponnulakshmi, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503776/
https://www.ncbi.nlm.nih.gov/pubmed/34675461
http://dx.doi.org/10.6026/97320630016753
Descripción
Sumario:Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further consideration.

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