Molecular docking analysis of COX-2 for potential inhibitors

Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further...

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Autores principales: Selvaraj, Jayaraman, Vishnupriya, Veeraraghavan, Sardar, Hussain, Balakrishna, Janardhana Papayya, Rex, Josephine, Mohan, Surapaneni Krishna, Vijayalakshmi, Periyasamy, Ponnulakshmi, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503776/
https://www.ncbi.nlm.nih.gov/pubmed/34675461
http://dx.doi.org/10.6026/97320630016753
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author Selvaraj, Jayaraman
Vishnupriya, Veeraraghavan
Sardar, Hussain
Balakrishna, Janardhana Papayya
Rex, Josephine
Mohan, Surapaneni Krishna
Vijayalakshmi, Periyasamy
Ponnulakshmi, Rajagopal
author_facet Selvaraj, Jayaraman
Vishnupriya, Veeraraghavan
Sardar, Hussain
Balakrishna, Janardhana Papayya
Rex, Josephine
Mohan, Surapaneni Krishna
Vijayalakshmi, Periyasamy
Ponnulakshmi, Rajagopal
author_sort Selvaraj, Jayaraman
collection PubMed
description Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further consideration.
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spelling pubmed-85037762021-10-20 Molecular docking analysis of COX-2 for potential inhibitors Selvaraj, Jayaraman Vishnupriya, Veeraraghavan Sardar, Hussain Balakrishna, Janardhana Papayya Rex, Josephine Mohan, Surapaneni Krishna Vijayalakshmi, Periyasamy Ponnulakshmi, Rajagopal Bioinformation Research Article Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further consideration. Biomedical Informatics 2020-10-31 /pmc/articles/PMC8503776/ /pubmed/34675461 http://dx.doi.org/10.6026/97320630016753 Text en © 2020 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Selvaraj, Jayaraman
Vishnupriya, Veeraraghavan
Sardar, Hussain
Balakrishna, Janardhana Papayya
Rex, Josephine
Mohan, Surapaneni Krishna
Vijayalakshmi, Periyasamy
Ponnulakshmi, Rajagopal
Molecular docking analysis of COX-2 for potential inhibitors
title Molecular docking analysis of COX-2 for potential inhibitors
title_full Molecular docking analysis of COX-2 for potential inhibitors
title_fullStr Molecular docking analysis of COX-2 for potential inhibitors
title_full_unstemmed Molecular docking analysis of COX-2 for potential inhibitors
title_short Molecular docking analysis of COX-2 for potential inhibitors
title_sort molecular docking analysis of cox-2 for potential inhibitors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503776/
https://www.ncbi.nlm.nih.gov/pubmed/34675461
http://dx.doi.org/10.6026/97320630016753
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