Cargando…

STING pathway expression in low‐grade serous carcinoma of the ovary: an unexpected therapeutic opportunity?

Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There is a need for new subtype‐specific treatment modalities, especially for women with widespread and chemo‐resistant disease. Stimulator of interferon genes (STING) is a part of the cGAS–...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huvila, Jutta, Cochrane, Dawn R, Ta, Monica, Chow, Christine, Greening, Kendall, Leung, Samuel, Karnezis, Anthony N, DiFeo, Analisa, Huntsman, David G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503889/ https://www.ncbi.nlm.nih.gov/pubmed/34138519 http://dx.doi.org/10.1002/cjp2.230

Ejemplares similares

The Molecular ‘Myc-anisms’ Behind Myc-Driven Tumorigenesis and the Relevant Myc-Directed Therapeutics
por: McAnulty, Jessica, et al.
Publicado: (2020)

miR-181a modulates circadian rhythm in immortalized bone marrow and adipose derived stromal cells and promotes differentiation through the regulation of PER3
por: Knarr, Matthew, et al.
Publicado: (2019)

Nucleo-Cytoplasmic Localization Domains Regulate Krüppel-Like Factor 6 (KLF6) Protein Stability and Tumor Suppressor Function
por: Rodríguez, Estefanía, et al.
Publicado: (2010)

Crowdsourcing Awareness: Exploration of the Ovarian Cancer Knowledge Gap through Amazon Mechanical Turk
por: Carter, Rebecca R., et al.
Publicado: (2014)

Oncogenes in high grade serous adenocarcinoma of the ovary
por: Manasa, Pacharla, et al.
Publicado: (2020)

Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
por: Jena, Saubhagya Kumar, et al.
Publicado: (2015)

MiR-181a targets STING to drive PARP inhibitor resistance in BRCA- mutated triple-negative breast cancer and ovarian cancer
por: Bustos, Matias A., et al.
Publicado: (2023)

CT features of low grade serous carcinoma of the ovary
por: Pannu, Harpreet K.
Publicado: (2015)

Educational Case: High-Grade Serous Carcinoma of the Ovary
por: Bunde, Sophia, et al.
Publicado: (2021)

Low-Grade Serous Carcinoma of the Ovary: The Current Status
por: Babaier, Abdulaziz, et al.
Publicado: (2022)

The Continuum of Serous Tumors of Low Malignant Potential and Low-Grade Serous Carcinomas of the Ovary
por: Wong, Kwong-Kwok, et al.
Publicado: (2007)

Altered glutamine metabolism in platinum resistant ovarian cancer
por: Hudson, Chantelle D., et al.
Publicado: (2016)

MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary
por: Lee, Cheng-Han, et al.
Publicado: (2009)

Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research
por: Hughes, Christopher S., et al.
Publicado: (2016)

Detection of Tumor-Specific PTPmu in Gynecological Cancer and Patient Derived Xenografts
por: Vincent, Jason, et al.
Publicado: (2021)

High Throughput Interrogation of Somatic Mutations in High Grade Serous Cancer of the Ovary
por: Matulonis, Ursula A., et al.
Publicado: (2011)

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
por: Ahmed, Ahmed Ashour, et al.
Publicado: (2010)

Impact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum
por: Gershenson, David M, et al.
Publicado: (2015)

Psammocarcinoma of ovary with serous cystadenofibroma of contralateral ovary: a case report
por: Jain, Deepali, et al.
Publicado: (2009)

Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance
por: Nagaraj, Anil Belur, et al.
Publicado: (2015)

Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary
por: Xu, Yan, et al.
Publicado: (2017)

Cytology positive pericardial effusion causing tamponade in patients with high grade serous carcinoma of the ovary
por: Kooy, Joni, et al.
Publicado: (2020)

Mesonephric-Like Carcinosarcoma of the Ovary Associated with Low-Grade Serous Carcinoma: A Case Report
por: d’Amati, Antonio, et al.
Publicado: (2021)

Cisplatin induces stemness in ovarian cancer
por: Wiechert, Andrew, et al.
Publicado: (2016)

Hepatic resection of metastatic tumor from serous cystadenocarcinoma of the ovary.
por: Lee, Jong Hoon, et al.
Publicado: (2002)

Multiple Breast Cancer Cell-Lines Derived from a Single Tumor Differ in Their Molecular Characteristics and Tumorigenic Potential
por: Mosoyan, Goar, et al.
Publicado: (2013)

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling
por: Knarr, Matthew, et al.
Publicado: (2020)

A Rare Case of Low-Grade Serous Cystadenocarcinoma of the Ovary in a Seventeen-Year-Old Woman
por: Rickards, John, et al.
Publicado: (2022)

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma
por: Cooke, Susanna L, et al.
Publicado: (2010)

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy
por: Motedayen Aval, Leila, et al.
Publicado: (2020)

STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer
por: Ghaffari, Abdi, et al.
Publicado: (2018)

Mechanisms of High-Grade Serous Carcinogenesis in the Fallopian Tube and Ovary: Current Hypotheses, Etiologic Factors, and Molecular Alterations
por: Otsuka, Isao
Publicado: (2021)

Imaging of serous psammomacarcinoma of ovary with subcutaneous deposits: A case report
por: Diwakar, Nagaraj, et al.
Publicado: (2011)

Cerebellar metastasis from serous adenocarcinoma of the ovary mimicking pilocytic astrocytoma
por: Tandon, Vivek, et al.
Publicado: (2012)

Fatal cardiac tamponade following cytoreductive surgery for serous carcinoma of the ovary
por: English, Emily, et al.
Publicado: (2015)

Cytology of peritoneal implants of borderline serous tumor of ovaries in ascitic fluid
por: Sharma, Sudha, et al.
Publicado: (2021)

A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
por: Senkowski, Wojciech, et al.
Publicado: (2023)

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas
por: Tone, Alicia A, et al.
Publicado: (2014)

Mistletoe Extract Viscum Fraxini-2 for Treatment of Advanced Hepatocellular Carcinoma: A Case Series
por: Lee, Richard T., et al.
Publicado: (2021)

Preparing for adulthood: thousands upon thousands of new cells are born in the hippocampus during puberty, and most survive with effortful learning
por: Curlik, Daniel M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_pket6dqu35fo3hsa8avfmvva4h