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Extracellular phosphate enhances the function of F508del-CFTR rescued by CFTR correctors

Background: The clinical response to cystic fibrosis transmembrane conductance regulator (CFTR) modulators varies between people with cystic fibrosis (CF) of the same genotype, in part through the action of solute carriers encoded by modifier genes. Here, we investigate whether phosphate transport b...

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Detalles Bibliográficos
Autores principales: Saint-Criq, Vinciane, Wang, Yiting, Delpiano, Livia, Lin, JinHeng, Sheppard, David N., Gray, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503924/
https://www.ncbi.nlm.nih.gov/pubmed/34020896
http://dx.doi.org/10.1016/j.jcf.2021.04.013