Cargando…

Cell-based therapies for retinal diseases: a review of clinical trials and direct to consumer “cell therapy” clinics

BACKGROUND: The retinal pigment epithelium (RPE) is implicated in the pathophysiology of many retinal degenerative diseases. This cell layer is also an ideal target for cell-based therapies. Several early phase clinical trials evaluating cell therapy approaches for diseases involving the RPE, such a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hinkle, John W., Mahmoudzadeh, Raziyeh, Kuriyan, Ajay E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504041/ https://www.ncbi.nlm.nih.gov/pubmed/34635174 http://dx.doi.org/10.1186/s13287-021-02546-9

Ejemplares similares

Schwann Cell-Mediated Preservation of Vision in Retinal Degenerative Diseases via the Reduction of Oxidative Stress: A Possible Mechanism
por: MAHMOUDZADEH, Raziyeh, et al.
Publicado: (2016)

Factors Associated with Fluctuations in Central Subfield Thickness in Patients with Diabetic Macular Edema Using Diabetic Retinopathy Clinical Research Protocols T and V
por: Torjani, Ava, et al.
Publicado: (2022)

Role of Schwann Cells in Preservation of Retinal Tissue Through Reduction of Oxidative Stress
por: Lashay, Alireza, et al.
Publicado: (2019)

Unproven stem cell therapy for macular degeneration
por: Ansari, Zubair A., et al.
Publicado: (2017)

Cell Replacement Therapy for Retinal and Optic Nerve Diseases: Cell Sources, Clinical Trials and Challenges
por: Coco-Martin, Rosa M., et al.
Publicado: (2021)

Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials
por: Labrador-Velandia, Sonia, et al.
Publicado: (2016)

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases
por: Cheng, Shun-Yun, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Based Therapy for Retinal Degenerative Diseases: Experimental Models and Clinical Trials
por: Holan, Vladimir, et al.
Publicado: (2021)

Online seminars as an information source for direct-to-consumer stem cell therapy
por: Hassoun, Mirna, et al.
Publicado: (2021)

Bacterial Dispersion Associated With Various Patient Face Mask Designs During Simulated Intravitreal Injections
por: Patel, Samir N., et al.
Publicado: (2021)

Comparison of Different Crosslinking Methods for Preparation of Docetaxel-loaded Albumin Nanoparticles
por: Niknejad, Hassan, et al.
Publicado: (2015)

Stem cell therapy in retinal diseases?
por: Siqueira, Rubens Camargo
Publicado: (2012)

Stem cell therapy in retinal diseases
por: Voisin, Audrey, et al.
Publicado: (2022)

Magnitude of Visual Acuity Change with ETDRS versus Snellen Testing in Clinical Trials: Implications for Clinic-Based Outcomes
por: Salabati, Mirataollah, et al.
Publicado: (2023)

Spectral domain optical coherence tomography imaging of subretinal bands associated with chronic retinal detachments
por: Kothari, Nikisha, et al.
Publicado: (2016)

Clinical applications of retinal gene therapies
por: Fu, Xin, et al.
Publicado: (2018)

Biomarkers in T cell therapy clinical trials
por: Kalos, Michael
Publicado: (2011)

Clinical trials for stem cell therapies
por: Trounson, Alan, et al.
Publicado: (2011)

Retinal Gene Therapy: Surgical Vector Delivery in the Translation to Clinical Trials
por: Ochakovski, G. Alex, et al.
Publicado: (2017)

Comparison of Medical and Consumer Wireless EEG Systems for Use in Clinical Trials
por: Ratti, Elena, et al.
Publicado: (2017)

Cell Therapies under Clinical Trials and Polarized Cell Therapies in Pre-Clinical Studies to Treat Ischemic Stroke and Neurological Diseases: A Literature Review
por: Hatakeyama, Masahiro, et al.
Publicado: (2020)

Management of Thyroid Eye Disease-Related Strabismus
por: Akbari, Mohammad Reza, et al.
Publicado: (2020)

Stem cell therapy for retinal diseases: update
por: Siqueira, Rubens Camargo
Publicado: (2011)

Cell-based therapy for retinal degenerative disease
por: Sharma, Y. R., et al.
Publicado: (2016)

Pluripotent stem cell therapy for retinal diseases
por: Ahmed, Ishrat, et al.
Publicado: (2021)

Analysis of Funding Source and Spin in the Reporting of Studies of Intravitreal Corticosteroid Therapy for Diabetic Macular Edema: A Systematic Review
por: Nithianandan, Harrish, et al.
Publicado: (2020)

Stem cell-derived retinal pigment epithelium cell therapy: Past and future directions
por: Rohowetz, Landon J., et al.
Publicado: (2023)

CAR T cell therapy in solid tumors: A review of current clinical trials
por: Patel, Urvi, et al.
Publicado: (2021)

From the Hypotheses to Clinical Evidence in Retinal Therapy
por: Beatson, Bradley, et al.
Publicado: (2021)

Pre-clinical to Clinical Translational Failures and Current Status of Clinical Trials in Stroke Therapy: A Brief Review
por: Dhir, Neha, et al.
Publicado: (2020)

The Clinical Trials of Mesenchymal Stromal Cells Therapy
por: Kouchakian, Mohammad Reza, et al.
Publicado: (2021)

Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials
por: Lalu, Manoj M., et al.
Publicado: (2012)

Update on Clinical Trials in Retinal Diseases
por: Kozak, Igor
Publicado: (2016)

Subluxed traumatic cataract: optical coherence tomography findings and clinical management
por: Kuriyan, Ajay E, et al.
Publicado: (2012)

Cell therapy approaches to autism: a review of clinical trial data
por: Price, Jack
Publicado: (2020)

Adoptive Cell Therapy in Hepatocellular Carcinoma: A Review of Clinical Trials
por: Ozer, Muhammet, et al.
Publicado: (2023)

An Engineering Platform for Clinical Application of Optogenetic Therapy in Retinal Degenerative Diseases
Publicado: (2023)

Cell therapies in the clinic
por: Wang, Lily Li‐Wen, et al.
Publicado: (2021)

Gene Therapy for Neurodegenerative Disease: Clinical Potential and Directions
por: Zhu, Xiaolin, et al.
Publicado: (2021)

Gene Therapy for Retinal Degenerative Diseases: Progress, Challenges, and Future Directions
por: Drag, Selina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_efhrgsnunir9s84ms7gqt2vhbc