Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity

BACKGROUND: SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) and neuropilin-1 (NRP1) receptors for entry into cells, and the serine protease TMPRSS2 for S protein priming. Inhibition of protease activity or the engagement with ACE2 and NRP1 receptors has been shown to be an effective strat...

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Detalles Bibliográficos
Autores principales: Saiz, Maria Laura, De Diego, Marta L., López-García, Darío, Corte-Iglesias, Viviana, Baragaño Raneros, Aroa, Astola, Ivan, Asensi, Victor, López-Larrea, Carlos, Suarez-Alvarez, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504098/
https://www.ncbi.nlm.nih.gov/pubmed/34635175
http://dx.doi.org/10.1186/s13148-021-01168-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504098/
https://www.ncbi.nlm.nih.gov/pubmed/34635175
http://dx.doi.org/10.1186/s13148-021-01168-5

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