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Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity

BACKGROUND: SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) and neuropilin-1 (NRP1) receptors for entry into cells, and the serine protease TMPRSS2 for S protein priming. Inhibition of protease activity or the engagement with ACE2 and NRP1 receptors has been shown to be an effective strat...

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Detalles Bibliográficos
Autores principales:	Saiz, Maria Laura, De Diego, Marta L., López-García, Darío, Corte-Iglesias, Viviana, Baragaño Raneros, Aroa, Astola, Ivan, Asensi, Victor, López-Larrea, Carlos, Suarez-Alvarez, Beatriz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504098/ https://www.ncbi.nlm.nih.gov/pubmed/34635175 http://dx.doi.org/10.1186/s13148-021-01168-5

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