Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors

BACKGROUND: Overexpression of FGFR1 is observed in numerous tumors and therefore this receptor constitutes an attractive molecular target for selective cancer treatment with cytotoxic conjugates. The success of cancer therapy with cytotoxic conjugates largely relies on the precise recognition of a c...

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Detalles Bibliográficos
Autores principales: Poźniak, Marta, Porębska, Natalia, Jastrzębski, Kamil, Krzyścik, Mateusz Adam, Kucińska, Marika, Zarzycka, Weronika, Barbach, Agnieszka, Zakrzewska, Małgorzata, Otlewski, Jacek, Miączyńska, Marta, Opaliński, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504119/
https://www.ncbi.nlm.nih.gov/pubmed/34635096
http://dx.doi.org/10.1186/s12929-021-00767-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504119/
https://www.ncbi.nlm.nih.gov/pubmed/34635096
http://dx.doi.org/10.1186/s12929-021-00767-x

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