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Causes and Consequences of Purifying Selection on SARS-CoV-2

Owing to a lag between a deleterious mutation’s appearance and its selective removal, gold-standard methods for mutation rate estimation assume no meaningful loss of mutations between parents and offspring. Indeed, from analysis of closely related lineages, in SARS-CoV-2, the Ka/Ks ratio was previou...

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Detalles Bibliográficos
Autores principales:	Morales, Atahualpa Castillo, Rice, Alan M, Ho, Alexander T, Mordstein, Christine, Mühlhausen, Stefanie, Watson, Samir, Cano, Laura, Young, Bethan, Kudla, Grzegorz, Hurst, Laurence D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504154/ https://www.ncbi.nlm.nih.gov/pubmed/34427640 http://dx.doi.org/10.1093/gbe/evab196

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