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p53-Induced Autophagy Regulates Chemotherapy and Radiotherapy Resistance in Multidrug Resistance Cancer Cells

BACKGROUND: Multidrug resistance (MDR), a major problem in oncology therapy, limits the effectiveness of anticancer drugs. Although p53 functions as a tumor suppressor, the associations between p53 status, autophagy, and MDR are complicated and conditional. METHOD:  In this report, p53-null human ov...

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Detalles Bibliográficos
Autores principales: Ma, Shumei, Kong, Dejuan, Fu, Xinxin, Liu, Lin, Liu, Yi, Xue, Chang, Tian, Zhujun, Li, Lan, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504250/
https://www.ncbi.nlm.nih.gov/pubmed/34646092
http://dx.doi.org/10.1177/15593258211048046