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Severe and critical COVID-19 in pregnancy: A case series from Montreal

BACKGROUND: Optimal obstetric management for women with coronavirus disease (COVID-19) is not known. We describe the management of six pregnant women requiring in-hospital care for severe COVID-19. METHODS: A retrospective chart review was conducted to identify pregnant women who tested positive for...

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Autores principales: Trahan, Marie-Julie, Malhamé, Isabelle, Mitric, Cristina, Simard, Camille, Lipes, Jed, Abenhaim, Haim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504303/
https://www.ncbi.nlm.nih.gov/pubmed/34646346
http://dx.doi.org/10.1177/1753495X21990213
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author Trahan, Marie-Julie
Malhamé, Isabelle
Mitric, Cristina
Simard, Camille
Lipes, Jed
Abenhaim, Haim A
author_facet Trahan, Marie-Julie
Malhamé, Isabelle
Mitric, Cristina
Simard, Camille
Lipes, Jed
Abenhaim, Haim A
author_sort Trahan, Marie-Julie
collection PubMed
description BACKGROUND: Optimal obstetric management for women with coronavirus disease (COVID-19) is not known. We describe the management of six pregnant women requiring in-hospital care for severe COVID-19. METHODS: A retrospective chart review was conducted to identify pregnant women who tested positive for Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) between 15 March and 30 June 2020. A subset of women meeting criteria for severe COVID-19 was included. RESULTS: Four women required non-invasive supplemental oxygen therapy and two required mechanical ventilation. Four women were discharged from hospital undelivered and two required preterm delivery. One woman had a pulmonary embolism, and two required re-admission for worsening symptoms. CONCLUSION: Management of pregnant women with severe COVID-19 is complex and should involve multidisciplinary expertise. Avoiding early delivery may be a safe option. We recommend an individualized approach to care, including careful consideration of the expected risks and benefits of expectant obstetric management versus delivery.
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spelling pubmed-85043032021-10-12 Severe and critical COVID-19 in pregnancy: A case series from Montreal Trahan, Marie-Julie Malhamé, Isabelle Mitric, Cristina Simard, Camille Lipes, Jed Abenhaim, Haim A Obstet Med Original Articles BACKGROUND: Optimal obstetric management for women with coronavirus disease (COVID-19) is not known. We describe the management of six pregnant women requiring in-hospital care for severe COVID-19. METHODS: A retrospective chart review was conducted to identify pregnant women who tested positive for Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) between 15 March and 30 June 2020. A subset of women meeting criteria for severe COVID-19 was included. RESULTS: Four women required non-invasive supplemental oxygen therapy and two required mechanical ventilation. Four women were discharged from hospital undelivered and two required preterm delivery. One woman had a pulmonary embolism, and two required re-admission for worsening symptoms. CONCLUSION: Management of pregnant women with severe COVID-19 is complex and should involve multidisciplinary expertise. Avoiding early delivery may be a safe option. We recommend an individualized approach to care, including careful consideration of the expected risks and benefits of expectant obstetric management versus delivery. SAGE Publications 2021-03-09 2021-09 /pmc/articles/PMC8504303/ /pubmed/34646346 http://dx.doi.org/10.1177/1753495X21990213 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Trahan, Marie-Julie
Malhamé, Isabelle
Mitric, Cristina
Simard, Camille
Lipes, Jed
Abenhaim, Haim A
Severe and critical COVID-19 in pregnancy: A case series from Montreal
title Severe and critical COVID-19 in pregnancy: A case series from Montreal
title_full Severe and critical COVID-19 in pregnancy: A case series from Montreal
title_fullStr Severe and critical COVID-19 in pregnancy: A case series from Montreal
title_full_unstemmed Severe and critical COVID-19 in pregnancy: A case series from Montreal
title_short Severe and critical COVID-19 in pregnancy: A case series from Montreal
title_sort severe and critical covid-19 in pregnancy: a case series from montreal
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504303/
https://www.ncbi.nlm.nih.gov/pubmed/34646346
http://dx.doi.org/10.1177/1753495X21990213
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