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Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination

The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-r...

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Detalles Bibliográficos
Autores principales: Crane, Phillip, Wong, Chiew, Mehta, Nilesh, Barlis, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504353/
https://www.ncbi.nlm.nih.gov/pubmed/34625447
http://dx.doi.org/10.1136/bcr-2021-246580
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author Crane, Phillip
Wong, Chiew
Mehta, Nilesh
Barlis, Peter
author_facet Crane, Phillip
Wong, Chiew
Mehta, Nilesh
Barlis, Peter
author_sort Crane, Phillip
collection PubMed
description The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-related adverse events. Notably, thrombotic thrombocytopaenia has been reported following ChAdOx1 nCov-19 (AstraZeneca) vaccination. We report the first known case of takotsubo (stress) cardiomyopathy 4 days after administration of the ChAdOx1 nCoV-19 vaccine in a 72-year-old man. While this condition remains one primarily seen in females, our case represents a new trigger that warrants careful consideration when assessing patients presenting with acute coronary syndromes following ChAdOx1 nCoV-19 vaccination.
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spelling pubmed-85043532021-10-22 Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination Crane, Phillip Wong, Chiew Mehta, Nilesh Barlis, Peter BMJ Case Rep Case Report The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-related adverse events. Notably, thrombotic thrombocytopaenia has been reported following ChAdOx1 nCov-19 (AstraZeneca) vaccination. We report the first known case of takotsubo (stress) cardiomyopathy 4 days after administration of the ChAdOx1 nCoV-19 vaccine in a 72-year-old man. While this condition remains one primarily seen in females, our case represents a new trigger that warrants careful consideration when assessing patients presenting with acute coronary syndromes following ChAdOx1 nCoV-19 vaccination. BMJ Publishing Group 2021-10-08 /pmc/articles/PMC8504353/ /pubmed/34625447 http://dx.doi.org/10.1136/bcr-2021-246580 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Crane, Phillip
Wong, Chiew
Mehta, Nilesh
Barlis, Peter
Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title_full Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title_fullStr Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title_full_unstemmed Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title_short Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
title_sort takotsubo (stress) cardiomyopathy after chadox1 ncov-19 vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504353/
https://www.ncbi.nlm.nih.gov/pubmed/34625447
http://dx.doi.org/10.1136/bcr-2021-246580
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