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Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination
The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504353/ https://www.ncbi.nlm.nih.gov/pubmed/34625447 http://dx.doi.org/10.1136/bcr-2021-246580 |
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author | Crane, Phillip Wong, Chiew Mehta, Nilesh Barlis, Peter |
author_facet | Crane, Phillip Wong, Chiew Mehta, Nilesh Barlis, Peter |
author_sort | Crane, Phillip |
collection | PubMed |
description | The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-related adverse events. Notably, thrombotic thrombocytopaenia has been reported following ChAdOx1 nCov-19 (AstraZeneca) vaccination. We report the first known case of takotsubo (stress) cardiomyopathy 4 days after administration of the ChAdOx1 nCoV-19 vaccine in a 72-year-old man. While this condition remains one primarily seen in females, our case represents a new trigger that warrants careful consideration when assessing patients presenting with acute coronary syndromes following ChAdOx1 nCoV-19 vaccination. |
format | Online Article Text |
id | pubmed-8504353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-85043532021-10-22 Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination Crane, Phillip Wong, Chiew Mehta, Nilesh Barlis, Peter BMJ Case Rep Case Report The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-related adverse events. Notably, thrombotic thrombocytopaenia has been reported following ChAdOx1 nCov-19 (AstraZeneca) vaccination. We report the first known case of takotsubo (stress) cardiomyopathy 4 days after administration of the ChAdOx1 nCoV-19 vaccine in a 72-year-old man. While this condition remains one primarily seen in females, our case represents a new trigger that warrants careful consideration when assessing patients presenting with acute coronary syndromes following ChAdOx1 nCoV-19 vaccination. BMJ Publishing Group 2021-10-08 /pmc/articles/PMC8504353/ /pubmed/34625447 http://dx.doi.org/10.1136/bcr-2021-246580 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Crane, Phillip Wong, Chiew Mehta, Nilesh Barlis, Peter Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title | Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title_full | Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title_fullStr | Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title_full_unstemmed | Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title_short | Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination |
title_sort | takotsubo (stress) cardiomyopathy after chadox1 ncov-19 vaccination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504353/ https://www.ncbi.nlm.nih.gov/pubmed/34625447 http://dx.doi.org/10.1136/bcr-2021-246580 |
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