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Large‐scale whole‐exome sequencing association study identifies FOXH1 gene and sphingolipid metabolism pathway influencing major depressive disorder

In the present study, we performed an exome‐wide investigation of the burden of rare disease‐causing variants for major depressive disorder (MDD) using 16,702 samples from UK biobank. Gene‐based association analysis and candidate gene prioritization analysis indicated that FOXH1 have significant ass...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Chen, Luan, Jiang, Bixuan, Sun, Yidan, Li, Mo, Wu, Hao, Zhang, Na, Sun, Xiaofang, Qin, Shengying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504519/
https://www.ncbi.nlm.nih.gov/pubmed/34633764
http://dx.doi.org/10.1111/cns.13733