Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer

We aimed to evaluate the extent of groin edema and its dosimetric effect in boosted inguinal lymph nodes (LN) for vulvar cancer patients. The level of edema was determined in 10 patients treated with radical radiotherapy. A dosimetric evaluation of six LNs in the patient with the maximum level of ed...

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Autores principales: Mohamed, Sandy, Fokdal, Lars, Assenholt, Marianne S., Kallehauge, Jesper, Lindegaard, Jacob C., Tanderup, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Technical Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504581/
https://www.ncbi.nlm.nih.gov/pubmed/34432357
http://dx.doi.org/10.1002/acm2.13372
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author Mohamed, Sandy
Fokdal, Lars
Assenholt, Marianne S.
Kallehauge, Jesper
Lindegaard, Jacob C.
Tanderup, Kari
author_facet Mohamed, Sandy
Fokdal, Lars
Assenholt, Marianne S.
Kallehauge, Jesper
Lindegaard, Jacob C.
Tanderup, Kari
author_sort Mohamed, Sandy
collection PubMed
description We aimed to evaluate the extent of groin edema and its dosimetric effect in boosted inguinal lymph nodes (LN) for vulvar cancer patients. The level of edema was determined in 10 patients treated with radical radiotherapy. A dosimetric evaluation of six LNs in the patient with the maximum level of edema was performed. The accumulated dose across CBCT fractions was acceptable for all six LNs (>94% of prescribed dose) even with the development of up to 13 mm of edema. The major contributor to fractional dose degradation was geographical displacement of the nodes. We suggest evaluation of edema on daily CBCT.
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spelling pubmed-85045812021-10-18 Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer Mohamed, Sandy Fokdal, Lars Assenholt, Marianne S. Kallehauge, Jesper Lindegaard, Jacob C. Tanderup, Kari J Appl Clin Med Phys Technical Notes We aimed to evaluate the extent of groin edema and its dosimetric effect in boosted inguinal lymph nodes (LN) for vulvar cancer patients. The level of edema was determined in 10 patients treated with radical radiotherapy. A dosimetric evaluation of six LNs in the patient with the maximum level of edema was performed. The accumulated dose across CBCT fractions was acceptable for all six LNs (>94% of prescribed dose) even with the development of up to 13 mm of edema. The major contributor to fractional dose degradation was geographical displacement of the nodes. We suggest evaluation of edema on daily CBCT. John Wiley and Sons Inc. 2021-08-25 /pmc/articles/PMC8504581/ /pubmed/34432357 http://dx.doi.org/10.1002/acm2.13372 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Notes
Mohamed, Sandy
Fokdal, Lars
Assenholt, Marianne S.
Kallehauge, Jesper
Lindegaard, Jacob C.
Tanderup, Kari
Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title_full Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title_fullStr Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title_full_unstemmed Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title_short Dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
title_sort dosimetric impact of edema on inguinal lymph node boost in locally advanced vulvar cancer
topic Technical Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504581/
https://www.ncbi.nlm.nih.gov/pubmed/34432357
http://dx.doi.org/10.1002/acm2.13372
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