Cargando…
Nontoxic electron collimators
PURPOSE: The goal of this work was to develop and test nontoxic electron collimation technologies for clinical use. METHODS: Two novel technologies were investigated: tungsten‐silicone composite and 3D printed electron cutouts. Transmission, dose uniformity, and profiles were measured for the tungst...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504586/ https://www.ncbi.nlm.nih.gov/pubmed/34480841 http://dx.doi.org/10.1002/acm2.13398 |
_version_ | 1784581348564926464 |
---|---|
author | Breitkreutz, Dylan Yamabe Skinner, Lawrie Lo, Stephanie Yu, Amy |
author_facet | Breitkreutz, Dylan Yamabe Skinner, Lawrie Lo, Stephanie Yu, Amy |
author_sort | Breitkreutz, Dylan Yamabe |
collection | PubMed |
description | PURPOSE: The goal of this work was to develop and test nontoxic electron collimation technologies for clinical use. METHODS: Two novel technologies were investigated: tungsten‐silicone composite and 3D printed electron cutouts. Transmission, dose uniformity, and profiles were measured for the tungsten‐silicone. Surface dose, relative dose output, and field size were measured for the 3D printed cutouts and compared with the standard cerrobend cutouts in current clinical use. Quality assurance tests including mass measurements, Megavoltage (MV) imaging, and drop testing were developed for the 3D printed cutouts as a guide to safe clinical implementation. RESULTS: Dose profiles of the flexible tungsten‐silicone skin shields had an 80–20 penumbra values of 2–3 mm compared to 7–8 mm for cerrobend. In MV transmission image measurements of the tungsten‐silicone, 80% of the pixels had a transmission value within 2% of the mean. An ∼90% reduction in electron intensity was measured for 6 MeV and a 6.4 mm thickness of tungsten‐silicone and 12.7 mm thickness for 16 MeV. The maximum difference in 3D printed cutout versus cerrobend output, surface dose, and full width at half‐maximum (FWHM) was 1.7%, 1.2%, and 1.5%, respectively, for the 10 cm × 10 cm cutouts. CONCLUSIONS: Both flexible tungsten‐silicone and 3D printed cutouts were found to be feasible for clinical use. The flexible tungsten‐silicone was of adequate density, flexibility, and uniformity to serve as skin shields for electron therapy. The 3D printed cutouts were dosimetrically equivalent to standard cerrobend cutouts and were robust enough for handling in the clinical environment. |
format | Online Article Text |
id | pubmed-8504586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85045862021-10-18 Nontoxic electron collimators Breitkreutz, Dylan Yamabe Skinner, Lawrie Lo, Stephanie Yu, Amy J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: The goal of this work was to develop and test nontoxic electron collimation technologies for clinical use. METHODS: Two novel technologies were investigated: tungsten‐silicone composite and 3D printed electron cutouts. Transmission, dose uniformity, and profiles were measured for the tungsten‐silicone. Surface dose, relative dose output, and field size were measured for the 3D printed cutouts and compared with the standard cerrobend cutouts in current clinical use. Quality assurance tests including mass measurements, Megavoltage (MV) imaging, and drop testing were developed for the 3D printed cutouts as a guide to safe clinical implementation. RESULTS: Dose profiles of the flexible tungsten‐silicone skin shields had an 80–20 penumbra values of 2–3 mm compared to 7–8 mm for cerrobend. In MV transmission image measurements of the tungsten‐silicone, 80% of the pixels had a transmission value within 2% of the mean. An ∼90% reduction in electron intensity was measured for 6 MeV and a 6.4 mm thickness of tungsten‐silicone and 12.7 mm thickness for 16 MeV. The maximum difference in 3D printed cutout versus cerrobend output, surface dose, and full width at half‐maximum (FWHM) was 1.7%, 1.2%, and 1.5%, respectively, for the 10 cm × 10 cm cutouts. CONCLUSIONS: Both flexible tungsten‐silicone and 3D printed cutouts were found to be feasible for clinical use. The flexible tungsten‐silicone was of adequate density, flexibility, and uniformity to serve as skin shields for electron therapy. The 3D printed cutouts were dosimetrically equivalent to standard cerrobend cutouts and were robust enough for handling in the clinical environment. John Wiley and Sons Inc. 2021-09-04 /pmc/articles/PMC8504586/ /pubmed/34480841 http://dx.doi.org/10.1002/acm2.13398 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Breitkreutz, Dylan Yamabe Skinner, Lawrie Lo, Stephanie Yu, Amy Nontoxic electron collimators |
title | Nontoxic electron collimators |
title_full | Nontoxic electron collimators |
title_fullStr | Nontoxic electron collimators |
title_full_unstemmed | Nontoxic electron collimators |
title_short | Nontoxic electron collimators |
title_sort | nontoxic electron collimators |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504586/ https://www.ncbi.nlm.nih.gov/pubmed/34480841 http://dx.doi.org/10.1002/acm2.13398 |
work_keys_str_mv | AT breitkreutzdylanyamabe nontoxicelectroncollimators AT skinnerlawrie nontoxicelectroncollimators AT lostephanie nontoxicelectroncollimators AT yuamy nontoxicelectroncollimators |