Cargando…
Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractio...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504599/ https://www.ncbi.nlm.nih.gov/pubmed/34554605 http://dx.doi.org/10.1002/acm2.13428 |
_version_ | 1784581351737917440 |
---|---|
author | Ju, Eunbin Heo, Eun Jeong Park, Chun Gun Kim, Minseok Kim, Kwang Hyeon Shim, Jang Bo Park, Young Je Lee, Nam Kwon Kim, Chul Yong Lee, Suk |
author_facet | Ju, Eunbin Heo, Eun Jeong Park, Chun Gun Kim, Minseok Kim, Kwang Hyeon Shim, Jang Bo Park, Young Je Lee, Nam Kwon Kim, Chul Yong Lee, Suk |
author_sort | Ju, Eunbin |
collection | PubMed |
description | PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractionated SIB, were recruited. All cases were planned using Halcyon(TM) comprising a dual‐layer MLC (DL‐MLC) and VitalBeam(®) with a Millennium 120 MLC (VB‐MLC). For the PTVs, the quality of coverage (QC), conformity index (CI), and homogeneity index (HI) were calculated for each plan. The dosimetric differences between the two treatment plans were statistically compared using the Wilcoxon signed‐rank test (p < 0.05). To evaluate delivery efficiency, the average delivery time for each patient's treatment plan was recorded and compared. RESULTS: For the PTVs, the two plans (DL‐MLC and VB‐MLC) were comparable in terms of the QC, CI, and HI. However, V (30Gy) and D (mean) for the heart in the DL‐MLC plan were significantly reduced by 0.49% and 14.6%, respectively, compared with those in the VB‐MLC plan (p < 0.05). The D (mean) value for the ipsilateral lung in the DL‐MLC plan significantly decreased by 5.5%, compared with that in the VB‐MLC plan (p < 0.05). In addition, the delivery times for the DL‐MLC and VB‐MLC plans were 79 ± 10 and 101 ± 11 s, respectively. CONCLUSIONS: DL‐MLC plans were found to improve OAR sparing. In particular, when treating left‐sided breast cancer via DL‐MLC plans, the risk of heart toxicity is expected to be reduced. |
format | Online Article Text |
id | pubmed-8504599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85045992021-10-18 Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer Ju, Eunbin Heo, Eun Jeong Park, Chun Gun Kim, Minseok Kim, Kwang Hyeon Shim, Jang Bo Park, Young Je Lee, Nam Kwon Kim, Chul Yong Lee, Suk J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractionated SIB, were recruited. All cases were planned using Halcyon(TM) comprising a dual‐layer MLC (DL‐MLC) and VitalBeam(®) with a Millennium 120 MLC (VB‐MLC). For the PTVs, the quality of coverage (QC), conformity index (CI), and homogeneity index (HI) were calculated for each plan. The dosimetric differences between the two treatment plans were statistically compared using the Wilcoxon signed‐rank test (p < 0.05). To evaluate delivery efficiency, the average delivery time for each patient's treatment plan was recorded and compared. RESULTS: For the PTVs, the two plans (DL‐MLC and VB‐MLC) were comparable in terms of the QC, CI, and HI. However, V (30Gy) and D (mean) for the heart in the DL‐MLC plan were significantly reduced by 0.49% and 14.6%, respectively, compared with those in the VB‐MLC plan (p < 0.05). The D (mean) value for the ipsilateral lung in the DL‐MLC plan significantly decreased by 5.5%, compared with that in the VB‐MLC plan (p < 0.05). In addition, the delivery times for the DL‐MLC and VB‐MLC plans were 79 ± 10 and 101 ± 11 s, respectively. CONCLUSIONS: DL‐MLC plans were found to improve OAR sparing. In particular, when treating left‐sided breast cancer via DL‐MLC plans, the risk of heart toxicity is expected to be reduced. John Wiley and Sons Inc. 2021-09-23 /pmc/articles/PMC8504599/ /pubmed/34554605 http://dx.doi.org/10.1002/acm2.13428 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Ju, Eunbin Heo, Eun Jeong Park, Chun Gun Kim, Minseok Kim, Kwang Hyeon Shim, Jang Bo Park, Young Je Lee, Nam Kwon Kim, Chul Yong Lee, Suk Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title | Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title_full | Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title_fullStr | Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title_full_unstemmed | Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title_short | Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
title_sort | dosimetric comparison of vitalbeam(®) and halcyon(tm) 2.0 for hypofractionated vmat with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504599/ https://www.ncbi.nlm.nih.gov/pubmed/34554605 http://dx.doi.org/10.1002/acm2.13428 |
work_keys_str_mv | AT jueunbin dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT heoeunjeong dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT parkchungun dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT kimminseok dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT kimkwanghyeon dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT shimjangbo dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT parkyoungje dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT leenamkwon dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT kimchulyong dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer AT leesuk dosimetriccomparisonofvitalbeamandhalcyontm20forhypofractionatedvmatwithsimultaneousintegratedboosttreatmentofearlystageleftsidedbreastcancer |