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Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer

PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractio...

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Autores principales: Ju, Eunbin, Heo, Eun Jeong, Park, Chun Gun, Kim, Minseok, Kim, Kwang Hyeon, Shim, Jang Bo, Park, Young Je, Lee, Nam Kwon, Kim, Chul Yong, Lee, Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504599/
https://www.ncbi.nlm.nih.gov/pubmed/34554605
http://dx.doi.org/10.1002/acm2.13428
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author Ju, Eunbin
Heo, Eun Jeong
Park, Chun Gun
Kim, Minseok
Kim, Kwang Hyeon
Shim, Jang Bo
Park, Young Je
Lee, Nam Kwon
Kim, Chul Yong
Lee, Suk
author_facet Ju, Eunbin
Heo, Eun Jeong
Park, Chun Gun
Kim, Minseok
Kim, Kwang Hyeon
Shim, Jang Bo
Park, Young Je
Lee, Nam Kwon
Kim, Chul Yong
Lee, Suk
author_sort Ju, Eunbin
collection PubMed
description PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractionated SIB, were recruited. All cases were planned using Halcyon(TM) comprising a dual‐layer MLC (DL‐MLC) and VitalBeam(®) with a Millennium 120 MLC (VB‐MLC). For the PTVs, the quality of coverage (QC), conformity index (CI), and homogeneity index (HI) were calculated for each plan. The dosimetric differences between the two treatment plans were statistically compared using the Wilcoxon signed‐rank test (p < 0.05). To evaluate delivery efficiency, the average delivery time for each patient's treatment plan was recorded and compared. RESULTS: For the PTVs, the two plans (DL‐MLC and VB‐MLC) were comparable in terms of the QC, CI, and HI. However, V (30Gy) and D (mean) for the heart in the DL‐MLC plan were significantly reduced by 0.49% and 14.6%, respectively, compared with those in the VB‐MLC plan (p < 0.05). The D (mean) value for the ipsilateral lung in the DL‐MLC plan significantly decreased by 5.5%, compared with that in the VB‐MLC plan (p < 0.05). In addition, the delivery times for the DL‐MLC and VB‐MLC plans were 79 ± 10 and 101 ± 11 s, respectively. CONCLUSIONS: DL‐MLC plans were found to improve OAR sparing. In particular, when treating left‐sided breast cancer via DL‐MLC plans, the risk of heart toxicity is expected to be reduced.
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spelling pubmed-85045992021-10-18 Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer Ju, Eunbin Heo, Eun Jeong Park, Chun Gun Kim, Minseok Kim, Kwang Hyeon Shim, Jang Bo Park, Young Je Lee, Nam Kwon Kim, Chul Yong Lee, Suk J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: This study compared the quality of treatment plans for early‐stage, left‐sided breast cancer, as planned for and delivered by the Halcyon(TM) and VitalBeam(®). MATERIALS AND METHODS: Fifteen patients diagnosed with early‐stage left‐sided breast cancer, who had received VMAT with hypofractionated SIB, were recruited. All cases were planned using Halcyon(TM) comprising a dual‐layer MLC (DL‐MLC) and VitalBeam(®) with a Millennium 120 MLC (VB‐MLC). For the PTVs, the quality of coverage (QC), conformity index (CI), and homogeneity index (HI) were calculated for each plan. The dosimetric differences between the two treatment plans were statistically compared using the Wilcoxon signed‐rank test (p < 0.05). To evaluate delivery efficiency, the average delivery time for each patient's treatment plan was recorded and compared. RESULTS: For the PTVs, the two plans (DL‐MLC and VB‐MLC) were comparable in terms of the QC, CI, and HI. However, V (30Gy) and D (mean) for the heart in the DL‐MLC plan were significantly reduced by 0.49% and 14.6%, respectively, compared with those in the VB‐MLC plan (p < 0.05). The D (mean) value for the ipsilateral lung in the DL‐MLC plan significantly decreased by 5.5%, compared with that in the VB‐MLC plan (p < 0.05). In addition, the delivery times for the DL‐MLC and VB‐MLC plans were 79 ± 10 and 101 ± 11 s, respectively. CONCLUSIONS: DL‐MLC plans were found to improve OAR sparing. In particular, when treating left‐sided breast cancer via DL‐MLC plans, the risk of heart toxicity is expected to be reduced. John Wiley and Sons Inc. 2021-09-23 /pmc/articles/PMC8504599/ /pubmed/34554605 http://dx.doi.org/10.1002/acm2.13428 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ju, Eunbin
Heo, Eun Jeong
Park, Chun Gun
Kim, Minseok
Kim, Kwang Hyeon
Shim, Jang Bo
Park, Young Je
Lee, Nam Kwon
Kim, Chul Yong
Lee, Suk
Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title_full Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title_fullStr Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title_full_unstemmed Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title_short Dosimetric comparison of VitalBeam(®) and Halcyon(TM) 2.0 for hypofractionated VMAT with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
title_sort dosimetric comparison of vitalbeam(®) and halcyon(tm) 2.0 for hypofractionated vmat with simultaneous integrated boost treatment of early‐stage left‐sided breast cancer
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504599/
https://www.ncbi.nlm.nih.gov/pubmed/34554605
http://dx.doi.org/10.1002/acm2.13428
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