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Machine learning optimization of peptides for presentation by class II MHCs

SUMMARY: T cells play a critical role in cellular immune responses to pathogens and cancer and can be activated and expanded by Major Histocompatibility Complex (MHC)-presented antigens contained in peptide vaccines. We present a machine learning method to optimize the presentation of peptides by cl...

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Detalles Bibliográficos
Autores principales:	Dai, Zheng, Huisman, Brooke D, Zeng, Haoyang, Carter, Brandon, Jain, Siddhartha, Birnbaum, Michael E, Gifford, David K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504626/ https://www.ncbi.nlm.nih.gov/pubmed/33705522 http://dx.doi.org/10.1093/bioinformatics/btab131

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