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Fast identification of differential distributions in single-cell RNA-sequencing data with waddR

MOTIVATION: Single-cell gene expression distributions measured by single-cell RNA-sequencing (scRNA-seq) often display complex differences between samples. These differences are biologically meaningful but cannot be identified using standard methods for differential expression. RESULTS: Here, we der...

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Detalles Bibliográficos
Autores principales: Schefzik, Roman, Flesch, Julian, Goncalves, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504634/
https://www.ncbi.nlm.nih.gov/pubmed/33792651
http://dx.doi.org/10.1093/bioinformatics/btab226