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Phase II study of dacarbazine given with modern prophylactic anti-emetics and growth factor support to patients with metastatic, resistant soft tissue, and bone sarcoma
Historically, administration of dacarbazine to sarcoma patients was limited by frequent treat-ment-related nausea/vomiting and neutropenia. These toxicities are now largely preventable with contemporary antiemetics and growth factor support. In this single-arm, phase II study, dacarbazine 850 mg/m(2...
Autores principales: | Van Tine, Brian A, Weiss, Mia C, Hirbe, Angela C, Oppelt, Peter J, Abaricia, Sarah, Trinkaus, Kathryn, Luo, Jingqin, Berry, Shellie, Ruff, Tyler, Callahan, Cheryl, Toensikoetter, Jacqui, Ley, Jessica, Siegel, Marilyn J, Dehdashti, Farrokh, Siegel, Barry A, Adkins, Douglas R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504645/ https://www.ncbi.nlm.nih.gov/pubmed/34646430 http://dx.doi.org/10.1177/20363613211052498 |
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