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Enhancing breakpoint resolution with deep segmentation model: A general refinement method for read-depth based structural variant callers
Read-depths (RDs) are frequently used in identifying structural variants (SVs) from sequencing data. For existing RD-based SV callers, it is difficult for them to determine breakpoints in single-nucleotide resolution due to the noisiness of RD data and the bin-based calculation. In this paper, we pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504719/ https://www.ncbi.nlm.nih.gov/pubmed/34634042 http://dx.doi.org/10.1371/journal.pcbi.1009186 |