Cargando…

Design and conduct considerations for studies in patients with impaired renal function

An impaired renal function, including acute and chronic kidney disease and end‐stage renal disease, can be the result of aging, certain disease conditions, the use of some medications, or as a result of smoking. In patients with renal impairment (RI), the pharmacokinetics (PKs) of drugs or drug meta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ravenstijn, Paulien, Chetty, Manoranjenni, Manchandani, Pooja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504825/ https://www.ncbi.nlm.nih.gov/pubmed/33982447 http://dx.doi.org/10.1111/cts.13061

Ejemplares similares

Design and conduct considerations for studies in patients with hepatic impairment
por: Ravenstijn, Paulien, et al.
Publicado: (2022)

Are Standard Doses of Renally-Excreted Antiretrovirals in Older Patients Appropriate: A PBPK Study Comparing Exposures in the Elderly Population With Those in Renal Impairment
por: De Sousa Mendes, M., et al.
Publicado: (2019)

Potential benefit of vitamin D supplementation in people with respiratory illnesses, during the COVID‐19 pandemic
por: Chetty, Vasudevan V., et al.
Publicado: (2021)

Considerations for the design and conduct of human gut microbiota intervention studies relating to foods
por: Swann, J. R., et al.
Publicado: (2020)

Design and Conduct Considerations for First‐in‐Human Trials
por: Shen, Jie, et al.
Publicado: (2018)

Paliperidone Palmitate Long-Acting Injectable Given Intramuscularly in the Deltoid Versus the Gluteal Muscle: Are They Therapeutically Equivalent?
por: Ravenstijn, Paulien, et al.
Publicado: (2016)

Application of Physiologically Based Pharmacokinetic (PBPK) Modeling Within a Bayesian Framework to Identify Poor Metabolizers of Efavirenz (PM), Using a Test Dose of Efavirenz
por: Chetty, Manoranjenni, et al.
Publicado: (2018)

Efficacy and safety of paliperidone palmitate 3-month versus 1-month formulation in patients with schizophrenia: comparison between European and non-European population
por: Savitz, Adam J, et al.
Publicado: (2019)

Translational Model‐Informed Dose Selection for a Human Positron Emission Tomography Imaging Study of JNJ‐54175446, a P2X7 Receptor Antagonist
por: Xu, Yan, et al.
Publicado: (2019)

Are Physiologically Based Pharmacokinetic Models Reporting the Right C(max)? Central Venous Versus Peripheral Sampling Site
por: Musther, Helen, et al.
Publicado: (2015)

Key considerations for designing, conducting and analysing a cluster randomized trial
por: Hemming, Karla, et al.
Publicado: (2023)

HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention
por: Boily, Marie-Claude, et al.
Publicado: (2012)

Recent trends in the impurity profile of pharmaceuticals
por: Pilaniya, Kavita, et al.
Publicado: (2010)

Efficacy and Safety of Paliperidone Palmitate 3-Month Formulation for Patients with Schizophrenia: A Randomized, Multicenter, Double-Blind, Noninferiority Study
por: Savitz, Adam J., et al.
Publicado: (2016)

Prediction of the Pharmacokinetics, Pharmacodynamics, and Efficacy of a Monoclonal Antibody, Using a Physiologically Based Pharmacokinetic FcRn Model
por: Chetty, Manoranjenni, et al.
Publicado: (2015)

Maintenance dose conversion between oral risperidone and paliperidone palmitate 1 month: Practical guidance based on pharmacokinetic simulations
por: Russu, Alberto, et al.
Publicado: (2018)

Scientific Considerations for Evaluating Cancer Bioassays Conducted by the Ramazzini Institute
por: Gift, Jeffrey S., et al.
Publicado: (2013)

Considerations of trial design and conduct in behavioral interventions for the management of chronic pain in adults
por: Edmond, Sara N., et al.
Publicado: (2018)

Renal artery thrombosis in COVID-19
por: Acharya, Sudeep, et al.
Publicado: (2020)

Experimental design considerations in microbiota/inflammation studies
por: Moore, Robert J, et al.
Publicado: (2016)

Drug-induced impairment of renal function
por: Pazhayattil, George Sunny, et al.
Publicado: (2014)

Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease
por: Ravenstijn, Paulien GM, et al.
Publicado: (2012)

Considerations for Conducting Bring Your Own “Device” (BYOD) Clinical Studies
por: Demanuele, Charmaine, et al.
Publicado: (2022)

Practicalities and Research Considerations for Conducting Childhood Obesity Prevention Interventions with Families
por: Morgan, Philip J., et al.
Publicado: (2016)

Conduction, Evaluation, and Future Considerations for an Obesity Educator Training Program in Korea
por: Kim, Yang-Hyun, et al.
Publicado: (2017)

Estimation of an Appropriate Dose of Trazodone for Pediatric Insomnia and the Potential for a Trazodone–Atomoxetine Interaction
por: Oggianu, Laura, et al.
Publicado: (2020)

2015 Behavioral clinical trials: Considerations for design and conduct using the new NIH study protocol template
por: Murphy, Susan L., et al.
Publicado: (2018)

Methodological Considerations in Conducting an Olfactory fMRI Study
por: Vedaei, Faezeh, et al.
Publicado: (2013)

South Africa’s capacity to conduct antimicrobial stewardship
por: Chetty, Sarentha
Publicado: (2021)

Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [(18)F]JNJ-64413739 PET and MRA-driven image derived input function
por: Mertens, Nathalie, et al.
Publicado: (2021)

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability
por: Chetty, Manoranjenni, et al.
Publicado: (2014)

Ethical considerations in conducting surgical research in severe complicated intra-abdominal sepsis
por: Doig, Christopher J., et al.
Publicado: (2019)

PBPK Modeling of Azithromycin Systemic Exposure in a Roux-en-Y Gastric Bypass Surgery Patient Population
por: Avvari, Suvarchala Kiranmai, et al.
Publicado: (2023)

Dental informed consent challenges and considerations for cognitively impaired patients
por: Alsaleh, Ahmed, et al.
Publicado: (2021)

Immunological and Toxicological Considerations for the Design of Liposomes
por: Inglut, Collin T., et al.
Publicado: (2020)

Clinical considerations for the design of PROTACs in cancer
por: Nieto-Jiménez, Cristina, et al.
Publicado: (2022)

A review of cardiovascular and renal function monitoring: a consideration of older adults with HIV
por: Kebodeaux, Clark D, et al.
Publicado: (2013)

PB1884: ENGAGING INNATE IMMUNITY: A PHASE 1 DOSE ESCALATION STUDY TO ASSESS SAFETY AND TOLERABILITY OF AFM28 MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY CD123-POSITIVE ACUTE MYELOID LEUKEMIA (AML)
por: Arnan, Montserrat, et al.
Publicado: (2023)

Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)
por: Hoffmann, Ricarda M., et al.
Publicado: (2017)

Value, challenges and practical considerations when designing, conducting and analysing a longitudinal qualitative study in family medicine
por: Wanat, Marta, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1njgkkqki21o7figujkjf46lt7