Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation study

The liver is the primary organ responsible for clearing most drugs from the body and thus determines systemic drug concentrations over time. Drug clearance by the liver appears to be directly related to organ size. In children, organ size changes as children age and grow. Liver volume has been corre...

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Detalles Bibliográficos
Autores principales: Hosey‐Cojocari, Chelsea, Chan, Sherwin S., Friesen, Chance S., Robinson, Amie, Williams, Veronica, Swanson, Erica, O’Toole, Daniel, Radford, Jansynn, Mardis, Neil, Johnson, Trevor N., Leeder, J. Steven, Shakhnovich, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504846/
https://www.ncbi.nlm.nih.gov/pubmed/33982422
http://dx.doi.org/10.1111/cts.13059

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