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Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence

Down syndrome (DS) is a unique genetic disease caused by the presence of an extra copy of chromosome 21, which carries four of the six interferon receptor (IFN-R) genes on its long arm. Recent studies reporting higher levels of interferon-stimulated gene (ISG) expression in primary immune cells stud...

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Detalles Bibliográficos
Autores principales:	Chung, Howard, Green, Peter H R, Wang, Timothy C, Kong, Xiao-Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504936/ https://www.ncbi.nlm.nih.gov/pubmed/34675597 http://dx.doi.org/10.2147/JIR.S280953

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