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Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments

Tin-117 m (Sn-117m) is used to treat dogs with osteoarthritic joints by radiosynoviorthesis. The decay process for Sn-117m is internal conversion wherein IC electrons and auger electrons provide the therapeutic effect. Additionally, the most prominent gamma emission is 158.6 keV. The effective dose...

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Autores principales: Arno, Matthew G., Smith, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505144/
https://www.ncbi.nlm.nih.gov/pubmed/34411058
http://dx.doi.org/10.1097/HP.0000000000001448
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author Arno, Matthew G.
Smith, Chad
author_facet Arno, Matthew G.
Smith, Chad
author_sort Arno, Matthew G.
collection PubMed
description Tin-117 m (Sn-117m) is used to treat dogs with osteoarthritic joints by radiosynoviorthesis. The decay process for Sn-117m is internal conversion wherein IC electrons and auger electrons provide the therapeutic effect. Additionally, the most prominent gamma emission is 158.6 keV. The effective dose rate received by a person interacting at close distances with a treated dog is needed to determine the person's total dose and thus regulatory compliance. Simple measurement of the dose rate at a given distance does not provide an accurate measurement of the effective dose to a person due to the non-uniform nature of the radiation field at close distances. MNCP models of the interactions of five ages of humans at three distances were created to determine the effective dose rates using the methodology from NRC Regulatory Guide 8.40. Ratios of the effective dose rate to the person to the measured dose rate at 1 m from the same source were calculated.
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spelling pubmed-85051442021-10-13 Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments Arno, Matthew G. Smith, Chad Health Phys Papers Tin-117 m (Sn-117m) is used to treat dogs with osteoarthritic joints by radiosynoviorthesis. The decay process for Sn-117m is internal conversion wherein IC electrons and auger electrons provide the therapeutic effect. Additionally, the most prominent gamma emission is 158.6 keV. The effective dose rate received by a person interacting at close distances with a treated dog is needed to determine the person's total dose and thus regulatory compliance. Simple measurement of the dose rate at a given distance does not provide an accurate measurement of the effective dose to a person due to the non-uniform nature of the radiation field at close distances. MNCP models of the interactions of five ages of humans at three distances were created to determine the effective dose rates using the methodology from NRC Regulatory Guide 8.40. Ratios of the effective dose rate to the person to the measured dose rate at 1 m from the same source were calculated. Lippincott Williams & Wilkins 2021-11 2021-08-18 /pmc/articles/PMC8505144/ /pubmed/34411058 http://dx.doi.org/10.1097/HP.0000000000001448 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Health Physics Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Papers
Arno, Matthew G.
Smith, Chad
Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title_full Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title_fullStr Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title_full_unstemmed Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title_short Age-dependent Radiation Dose Rates from Canine Sn-117m Treatments
title_sort age-dependent radiation dose rates from canine sn-117m treatments
topic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505144/
https://www.ncbi.nlm.nih.gov/pubmed/34411058
http://dx.doi.org/10.1097/HP.0000000000001448
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