Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder

Bipolar disorder (BD) is a severe mental disorder characterized by repeated mood swings. Although genetic factors are collectively associated with the etiology of BD, the underlying molecular mechanisms, particularly how environmental factors affect the brain, remain largely unknown. We performed pr...

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Detalles Bibliográficos
Autores principales: Bundo, Miki, Ueda, Junko, Nakachi, Yutaka, Kasai, Kiyoto, Kato, Tadafumi, Iwamoto, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505249/
https://www.ncbi.nlm.nih.gov/pubmed/33875800
http://dx.doi.org/10.1038/s41380-021-01079-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505249/
https://www.ncbi.nlm.nih.gov/pubmed/33875800
http://dx.doi.org/10.1038/s41380-021-01079-0

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