Cargando…

Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder

Bipolar disorder (BD) is a severe mental disorder characterized by repeated mood swings. Although genetic factors are collectively associated with the etiology of BD, the underlying molecular mechanisms, particularly how environmental factors affect the brain, remain largely unknown. We performed pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bundo, Miki, Ueda, Junko, Nakachi, Yutaka, Kasai, Kiyoto, Kato, Tadafumi, Iwamoto, Kazuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505249/ https://www.ncbi.nlm.nih.gov/pubmed/33875800 http://dx.doi.org/10.1038/s41380-021-01079-0

Ejemplares similares

Cell type‐specific DNA methylation analysis of the prefrontal cortex of patients with schizophrenia
por: Ueda, Junko, et al.
Publicado: (2021)

DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice
por: Murata, Yui, et al.
Publicado: (2017)

A systematic evaluation of whole genome amplification of bisulfite-modified DNA
por: Bundo, Miki, et al.
Publicado: (2012)

Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA
por: Sugawara, Hiroko, et al.
Publicado: (2022)

Comprehensive DNA Methylation Analysis of Human Neuroblastoma Cells Treated With Haloperidol and Risperidone
por: Du, Jianbin, et al.
Publicado: (2021)

PM497. Epigenetic status of LINE-1 promoters in neurons and non-neurons
por: Watanabe, Risa, et al.
Publicado: (2016)

DNA methylation in schizophrenia: progress and challenges of epigenetic studies
por: Nishioka, Masaki, et al.
Publicado: (2012)

Identification of somatic mutations in monozygotic twins discordant for psychiatric disorders
por: Nishioka, Masaki, et al.
Publicado: (2018)

PS52. Identifying common and distinctive epigenetic alterations between bipolar disorder and schizophrenia
por: Sugawara, Hiroko, et al.
Publicado: (2016)

Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies
por: Murata, Yui, et al.
Publicado: (2019)

Use of the Illumina EPIC methylation array for epigenomic research in the crab‐eating macaque (Macaca fascicularis)
por: Nakachi, Yutaka, et al.
Publicado: (2020)

PS41. Hypermethylation of SLC6A4 promoter in psychiatric disorders suppresses its expression.
por: Ikegame, Tempei, et al.
Publicado: (2016)

Detection of Chromosomal Structural Alterations in Single Cells by SNP Arrays: A Systematic Survey of Amplification Bias and Optimized Workflow
por: Iwamoto, Kazuya, et al.
Publicado: (2007)

Somatic mutations in the human brain: implications for psychiatric research
por: Nishioka, Masaki, et al.
Publicado: (2018)

PM371. Measurement of genomic copy number and DNA methylation levels of LINE-1 in the brains of poly(I:C) mouse model
por: Murata, Yui, et al.
Publicado: (2016)

A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia
por: Kubota-Sakashita, Mie, et al.
Publicado: (2014)

Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition
por: Kuroki, Ryota, et al.
Publicado: (2020)

Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins
por: Sugawara, H, et al.
Publicado: (2011)

Antipsychotics function as epigenetic age regulators in human neuroblastoma cells
por: Du, Jianbin, et al.
Publicado: (2022)

Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region
por: Ikegame, Tempei, et al.
Publicado: (2021)

Decreased Functional Connectivity of Vermis-Ventral Prefrontal Cortex in Bipolar Disorder
por: Li, Huanhuan, et al.
Publicado: (2021)

Epigenome-wide association study of DNA methylation in panic disorder
por: Shimada-Sugimoto, Mihoko, et al.
Publicado: (2017)

Shared functional impairment in the prefrontal cortex affects symptom severity across psychiatric disorders
por: Koike, Shinsuke, et al.
Publicado: (2022)

Decreased Expression of Sprouty2 in the Dorsolateral Prefrontal Cortex in Schizophrenia and Bipolar Disorder: A Correlation with BDNF Expression
por: Pillai, Anilkumar
Publicado: (2008)

Increased Expression in Dorsolateral Prefrontal Cortex of CAPON in Schizophrenia and Bipolar Disorder
por: Xu, Bin, et al.
Publicado: (2005)

Mass spectrometric analysis of prefrontal cortex proteins in schizophrenia and bipolar disorder
por: Lakhan, Shaheen E
Publicado: (2012)

S144. THE ASSOCIATION BETWEEN BRAIN ACTIVITY IN THE PREFRONTAL CORTEX AND DEMOGRAPHIC VARIABLES: A LARGE-SAMPLE FUNCTIONAL NEAR-INFRARED SPECTROSCOPY STUDY
por: Koike, Shinsuke, et al.
Publicado: (2018)

Decreased Chloride Channel Expression in the Dorsolateral Prefrontal Cortex in Schizophrenia
por: Sullivan, Courtney R., et al.
Publicado: (2015)

Decreased Medial Prefrontal Cortex Glutamate Levels in Perimenopausal Women
por: Yap, Sidney, et al.
Publicado: (2021)

CACNA1C hypermethylation is associated with bipolar disorder
por: Starnawska, A, et al.
Publicado: (2016)

The Functional Connectivity Between the Nucleus Accumbens and the Ventromedial Prefrontal Cortex as an Endophenotype for Bipolar Disorder
por: Whittaker, Joseph R., et al.
Publicado: (2018)

Genetic risk for bipolar disorder and schizophrenia predicts structure and function of the ventromedial prefrontal cortex
por: Abé, Christoph, et al.
Publicado: (2021)

Neuronal coding in the rodent prefrontal cortex
por: Kornienko, Olga, et al.
Publicado: (2013)

The prefrontal cortex /
por: Fuster, Joaquin M.
Publicado: (2008)

Network modules linking expression and methylation in prefrontal cortex of schizophrenia
por: Lin, Dongdong, et al.
Publicado: (2020)

Impaired Prefrontal Hemodynamic Maturation in Autism and Unaffected Siblings
por: Kawakubo, Yuki, et al.
Publicado: (2009)

Differential Neuregulin 1 Cleavage in the Prefrontal Cortex and Hippocampus in Schizophrenia and Bipolar Disorder: Preliminary Findings
por: Marballi, Ketan, et al.
Publicado: (2012)

Normal Metabolic Levels in Prefrontal Cortex in Euthymic Bipolar I Patients with and without Suicide Attempts
por: Rocha, Marlos Vasconcelos, et al.
Publicado: (2015)

Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex
por: Takeuchi, Hikaru, et al.
Publicado: (2021)

Neuronal congruency effects in macaque prefrontal cortex
por: Yao, Tao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1alc3o8p11fnt4sh159s22fesn