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Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men
While concurrent training is regularly used in older populations, the inverse relationship between fibre size and oxidative capacity suggests that endurance training in resistance-trained individuals may result in some loss of resistance training-induced gains in muscle mass, which may be more prono...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505308/ https://www.ncbi.nlm.nih.gov/pubmed/34390401 http://dx.doi.org/10.1007/s00421-021-04768-4 |
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author | Hendrickse, Paul William Venckunas, Tomas Platkevicius, Justinas Kairaitis, Ramutis Kamandulis, Sigitas Snieckus, Audrius Stasiulis, Arvydas Vitkiene, Jolanta Subocius, Andrejus Degens, Hans |
author_facet | Hendrickse, Paul William Venckunas, Tomas Platkevicius, Justinas Kairaitis, Ramutis Kamandulis, Sigitas Snieckus, Audrius Stasiulis, Arvydas Vitkiene, Jolanta Subocius, Andrejus Degens, Hans |
author_sort | Hendrickse, Paul William |
collection | PubMed |
description | While concurrent training is regularly used in older populations, the inverse relationship between fibre size and oxidative capacity suggests that endurance training in resistance-trained individuals may result in some loss of resistance training-induced gains in muscle mass, which may be more pronounced in older people. We investigated the impact of superimposed endurance training in younger (28.5 ± 4.8 years; n = 8) and older (67.5 ± 5.5 years; n = 7) highly resistance-trained men. Participants underwent a 10-week endurance cycling training programme consisting of five 6-min intervals at 75% max heart rate (HRmax) separated by 4-min intervals at 90% HRmax. The anatomical cross-sectional area (ACSA) of the thigh muscles, as determined with MRI, was 24% smaller in older compared to younger participants (p < 0.001). Although maximal oxygen consumption (VO(2)max) was also lower in the older group (p < 0.001), VO(2)max per kg body mass did not differ significantly between younger and older participants. Histological analyses of biopsies of the m. vastus lateralis showed that endurance training induced an increase in succinate dehydrogenase activity in both younger and older participants (p ≤ 0.043), and an increase in the number of capillaries around type I fibres (p = 0.017). The superimposed endurance training did not induce a significant decrease in thigh ACSA, fibre cross-sectional area, or knee extensor maximum voluntary isometric force. These observations indicate that adding endurance training to resistance training can lead to positive endurance-related adaptations without negative consequences for muscle size and strength in older and younger resistance-trained people. |
format | Online Article Text |
id | pubmed-8505308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-85053082021-10-19 Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men Hendrickse, Paul William Venckunas, Tomas Platkevicius, Justinas Kairaitis, Ramutis Kamandulis, Sigitas Snieckus, Audrius Stasiulis, Arvydas Vitkiene, Jolanta Subocius, Andrejus Degens, Hans Eur J Appl Physiol Original Article While concurrent training is regularly used in older populations, the inverse relationship between fibre size and oxidative capacity suggests that endurance training in resistance-trained individuals may result in some loss of resistance training-induced gains in muscle mass, which may be more pronounced in older people. We investigated the impact of superimposed endurance training in younger (28.5 ± 4.8 years; n = 8) and older (67.5 ± 5.5 years; n = 7) highly resistance-trained men. Participants underwent a 10-week endurance cycling training programme consisting of five 6-min intervals at 75% max heart rate (HRmax) separated by 4-min intervals at 90% HRmax. The anatomical cross-sectional area (ACSA) of the thigh muscles, as determined with MRI, was 24% smaller in older compared to younger participants (p < 0.001). Although maximal oxygen consumption (VO(2)max) was also lower in the older group (p < 0.001), VO(2)max per kg body mass did not differ significantly between younger and older participants. Histological analyses of biopsies of the m. vastus lateralis showed that endurance training induced an increase in succinate dehydrogenase activity in both younger and older participants (p ≤ 0.043), and an increase in the number of capillaries around type I fibres (p = 0.017). The superimposed endurance training did not induce a significant decrease in thigh ACSA, fibre cross-sectional area, or knee extensor maximum voluntary isometric force. These observations indicate that adding endurance training to resistance training can lead to positive endurance-related adaptations without negative consequences for muscle size and strength in older and younger resistance-trained people. Springer Berlin Heidelberg 2021-08-14 2021 /pmc/articles/PMC8505308/ /pubmed/34390401 http://dx.doi.org/10.1007/s00421-021-04768-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Hendrickse, Paul William Venckunas, Tomas Platkevicius, Justinas Kairaitis, Ramutis Kamandulis, Sigitas Snieckus, Audrius Stasiulis, Arvydas Vitkiene, Jolanta Subocius, Andrejus Degens, Hans Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title | Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title_full | Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title_fullStr | Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title_full_unstemmed | Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title_short | Endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
title_sort | endurance training-induced increase in muscle oxidative capacity without loss of muscle mass in younger and older resistance-trained men |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505308/ https://www.ncbi.nlm.nih.gov/pubmed/34390401 http://dx.doi.org/10.1007/s00421-021-04768-4 |
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