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Development of peptides targeting receptor binding site of the envelope glycoprotein to contain the West Nile virus infection

West Nile virus (WNV), re-emerging neurotropic flavivirus, can cross the blood–brain barrier (BBB) and cause fatal encephalitis and meningitis. Infection of the human brain microvascular endothelial cells (hBMECs), building blocks of the BBB, represents the pivotal step in neuroinvasion. Domain III...

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Detalles Bibliográficos
Autores principales: Mertinková, Patrícia, Mochnáčová, Evelína, Bhide, Katarína, Kulkarni, Amod, Tkáčová, Zuzana, Hruškovicová, Jana, Bhide, Mangesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505397/
https://www.ncbi.nlm.nih.gov/pubmed/34635758
http://dx.doi.org/10.1038/s41598-021-99696-w