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Development of peptides targeting receptor binding site of the envelope glycoprotein to contain the West Nile virus infection
West Nile virus (WNV), re-emerging neurotropic flavivirus, can cross the blood–brain barrier (BBB) and cause fatal encephalitis and meningitis. Infection of the human brain microvascular endothelial cells (hBMECs), building blocks of the BBB, represents the pivotal step in neuroinvasion. Domain III...
Autores principales: | Mertinková, Patrícia, Mochnáčová, Evelína, Bhide, Katarína, Kulkarni, Amod, Tkáčová, Zuzana, Hruškovicová, Jana, Bhide, Mangesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505397/ https://www.ncbi.nlm.nih.gov/pubmed/34635758 http://dx.doi.org/10.1038/s41598-021-99696-w |
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