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Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis

We determined the antitumor mechanism of apatinib in glioma using a patient-derived orthotopic xenograft (PDOX) glioma mouse model and glioblastoma (GBM) cell lines. The PDOX mouse model was established using tumor tissues from two glioma patients via single-cell injections. Sixteen mice were succes...

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Detalles Bibliográficos
Autores principales:	Yao, Hui, Liu, Jiangang, Zhang, Chi, Shao, Yunxiang, Li, Xuetao, Yu, Zhengquan, Huang, Yulun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505401/ https://www.ncbi.nlm.nih.gov/pubmed/34635636 http://dx.doi.org/10.1038/s41419-021-04225-2

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