Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms

The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to be disclosed. We here show that PLK1 recruitment by RSF1 at centromeres creates an activating phosphorylation on Thr236 in the activation loop...

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Detalles Bibliográficos
Autores principales: Lee, Ho-Soo, Min, Sunwoo, Jung, Ye-Eun, Chae, Sunyoung, Heo, June, Lee, Jae-Ho, Kim, TaeSoo, Kang, Ho-Chul, Nakanish, Makoto, Cha, Sun-Shin, Cho, Hyeseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505570/
https://www.ncbi.nlm.nih.gov/pubmed/34635673
http://dx.doi.org/10.1038/s41467-021-26220-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505570/
https://www.ncbi.nlm.nih.gov/pubmed/34635673
http://dx.doi.org/10.1038/s41467-021-26220-z

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