Cargando…
Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms
The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to be disclosed. We here show that PLK1 recruitment by RSF1 at centromeres creates an activating phosphorylation on Thr236 in the activation loop...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505570/ https://www.ncbi.nlm.nih.gov/pubmed/34635673 http://dx.doi.org/10.1038/s41467-021-26220-z |