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Metformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics

Penetration enhancement of metformin hydrochloride via its molecular dispersion in sorbitan monostearate microparticles is reported. This represents basic philosophy to maximize its entrapment for maximum penetration effect. Drug dispersion in sorbitan monostearate with different theoretical drug co...

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Detalles Bibliográficos
Autores principales:	Mady, Omar Y., Al-Shoubki, Adam A., Donia, Ahmed A., Qasim, Waseem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505636/ https://www.ncbi.nlm.nih.gov/pubmed/34635740 http://dx.doi.org/10.1038/s41598-021-99649-3

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