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An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins
Subtype C is the most prevalent clade of human immunodeficiency virus type 1 (HIV-1) worldwide. The reasons for this are poorly understood. Here, we demonstrate that a characteristic additional third nuclear factor κB (NF-κB) binding site in the long terminal repeat (LTR) promoter allows subtype C H...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505707/ https://www.ncbi.nlm.nih.gov/pubmed/34551301 http://dx.doi.org/10.1016/j.celrep.2021.109735 |