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Activity of Lymphostatin, A Lymphocyte Inhibitory Virulence Factor of Pathogenic Escherichia coli, is Dependent on a Cysteine Protease Motif

Lymphostatin (LifA) is a 366 kDa protein expressed by attaching & effacing Escherichia coli. It plays an important role in intestinal colonisation and inhibits the mitogen- and antigen-stimulated proliferation of lymphocytes and the synthesis of proinflammatory cytokines. LifA exhibits N-termina...

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Detalles Bibliográficos
Autores principales:	Bease, Andrew G., Blackburn, Elizabeth A., Chintoan-Uta, Cosmin, Webb, Shaun, Cassady-Cain, Robin L., Stevens, Mark P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505758/ https://www.ncbi.nlm.nih.gov/pubmed/34400181 http://dx.doi.org/10.1016/j.jmb.2021.167200

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