A novel rat model of vertebral inflammation–induced intervertebral disc degeneration mediated by activating cGAS/STING molecular pathway

In this study, we describe a new rat model of vertebral inflammation–induced caudal intervertebral disc degeneration (VI‐IVDD), in which IVD structure was not damaged and controllable segment and speed degeneration was achieved. VI‐IVDD model was obtained by placing lipopolysaccharide (LPS) in the c...

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Detalles Bibliográficos
Autores principales: Su, Qihang, Cai, Qiuchen, Li, Yongchao, Ge, Hengan, Zhang, Yuanzhen, Zhang, Yi, Tan, Jun, Li, Jie, Cheng, Biao, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505843/
https://www.ncbi.nlm.nih.gov/pubmed/34477314
http://dx.doi.org/10.1111/jcmm.16898

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