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Conserved Mechanism of Bicarbonate-Induced Sensitization of CatSper Channels in Human and Mouse Sperm

To fertilize an egg, mammalian sperm must undergo capacitation in the female genital tract. A key contributor to capacitation is the calcium (Ca(2+)) channel CatSper, which is activated by membrane depolarization and intracellular alkalinization. In mouse epididymal sperm, membrane depolarization by...

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Detalles Bibliográficos
Autores principales:	Ferreira, Juan J., Lybaert, Pascale, Puga-Molina, Lis C., Santi, Celia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505895/ https://www.ncbi.nlm.nih.gov/pubmed/34650979 http://dx.doi.org/10.3389/fcell.2021.733653

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