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Crosstalk Between Abnormal TSHR Signaling Activation and PTEN/PI3K in the Dedifferentiation of Thyroid Cancer Cells

Iodide uptake and the metabolism of thyroid cells are regulated by thyrotropin (TSH)-TSH receptor (TSHR) signaling. Thus, it is necessary to elevate serum TSH levels by T4 withdraw or rTSH administration to facilitate radioiodide ((131)I) therapy for differentiated thyroid cancer (DTC). However, non...

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Detalles Bibliográficos
Autores principales:	Feng, Fang, Han, Huiqin, Wu, Shuqi, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506026/ https://www.ncbi.nlm.nih.gov/pubmed/34650915 http://dx.doi.org/10.3389/fonc.2021.718578

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