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Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome

BACKGROUND: Pulmonary artery acceleration time (PAAT) is a reliable and non-invasive method for assessing pulmonary hemodynamics. To date, few studies have used PAAT to assess preterm infants, especially those with respiratory distress syndrome (RDS). This study aimed to assess changes in PAAT among...

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Autores principales: Wang, Liling, Zhang, Fengjuan, Li, Jiahui, Liu, Zhijie, Kou, Yan, Song, Yanting, Xu, Haiyan, Wang, Haiyan, Wang, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506067/
https://www.ncbi.nlm.nih.gov/pubmed/34733669
http://dx.doi.org/10.21037/tp-21-341
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author Wang, Liling
Zhang, Fengjuan
Li, Jiahui
Liu, Zhijie
Kou, Yan
Song, Yanting
Xu, Haiyan
Wang, Haiyan
Wang, Yulin
author_facet Wang, Liling
Zhang, Fengjuan
Li, Jiahui
Liu, Zhijie
Kou, Yan
Song, Yanting
Xu, Haiyan
Wang, Haiyan
Wang, Yulin
author_sort Wang, Liling
collection PubMed
description BACKGROUND: Pulmonary artery acceleration time (PAAT) is a reliable and non-invasive method for assessing pulmonary hemodynamics. To date, few studies have used PAAT to assess preterm infants, especially those with respiratory distress syndrome (RDS). This study aimed to assess changes in PAAT among preterm infants with RDS undergoing pulmonary surfactant (PS) therapy or not, and determine its potential effects on the pulmonary vascular disease (PVD) outcomes of preterm infants with RDS in the late postnatal period. METHODS: The risk of RDS was reviewed in 62 preterm infants with a gestational age of 26–31 weeks. The infants receiving PS therapy were allocated to the PS group, and the others were allocated to the control group. PAAT, right ventricular ejection time (RVET), and other ultrasonic parameters at 3 different time points after birth were studied and compared. RESULTS: Infants in the PS group had a significantly lower PAAT (52.7±5.9 vs. 59.6±8.7; P=0.001) and PAAT/RVET (0.30±0.03 vs. 0.33±0.03; P=0.001) than those in the control group at 36 weeks postmenstrual age (PMA). No significant increases in PAAT/RVET were detected at 3 different times for the PS group (P=0.117), but both PAAT and PAAT/RVET increased significantly with time after birth in the control group (P<0.001). CONCLUSIONS: Preterm infants with RDS might still have PVD in the late postnatal period and thus require long-term follow-up observation. PAAT appears to be a reliable non-invasive screening measure for evaluating pulmonary hemodynamics in preterm infants with RDS and late PVD.
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spelling pubmed-85060672021-11-02 Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome Wang, Liling Zhang, Fengjuan Li, Jiahui Liu, Zhijie Kou, Yan Song, Yanting Xu, Haiyan Wang, Haiyan Wang, Yulin Transl Pediatr Original Article BACKGROUND: Pulmonary artery acceleration time (PAAT) is a reliable and non-invasive method for assessing pulmonary hemodynamics. To date, few studies have used PAAT to assess preterm infants, especially those with respiratory distress syndrome (RDS). This study aimed to assess changes in PAAT among preterm infants with RDS undergoing pulmonary surfactant (PS) therapy or not, and determine its potential effects on the pulmonary vascular disease (PVD) outcomes of preterm infants with RDS in the late postnatal period. METHODS: The risk of RDS was reviewed in 62 preterm infants with a gestational age of 26–31 weeks. The infants receiving PS therapy were allocated to the PS group, and the others were allocated to the control group. PAAT, right ventricular ejection time (RVET), and other ultrasonic parameters at 3 different time points after birth were studied and compared. RESULTS: Infants in the PS group had a significantly lower PAAT (52.7±5.9 vs. 59.6±8.7; P=0.001) and PAAT/RVET (0.30±0.03 vs. 0.33±0.03; P=0.001) than those in the control group at 36 weeks postmenstrual age (PMA). No significant increases in PAAT/RVET were detected at 3 different times for the PS group (P=0.117), but both PAAT and PAAT/RVET increased significantly with time after birth in the control group (P<0.001). CONCLUSIONS: Preterm infants with RDS might still have PVD in the late postnatal period and thus require long-term follow-up observation. PAAT appears to be a reliable non-invasive screening measure for evaluating pulmonary hemodynamics in preterm infants with RDS and late PVD. AME Publishing Company 2021-09 /pmc/articles/PMC8506067/ /pubmed/34733669 http://dx.doi.org/10.21037/tp-21-341 Text en 2021 Translational Pediatrics. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Wang, Liling
Zhang, Fengjuan
Li, Jiahui
Liu, Zhijie
Kou, Yan
Song, Yanting
Xu, Haiyan
Wang, Haiyan
Wang, Yulin
Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title_full Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title_fullStr Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title_full_unstemmed Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title_short Using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
title_sort using pulmonary artery acceleration time to evaluate pulmonary hemodynamic changes on preterm infants with respiratory distress syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506067/
https://www.ncbi.nlm.nih.gov/pubmed/34733669
http://dx.doi.org/10.21037/tp-21-341
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