Cargando…
Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond
The transcription factor p73 is a structural and functional homolog of TP53, the most famous and frequently mutated tumor-suppressor gene. The TP73 gene can synthesize an overwhelming number of isoforms via splicing events in 5′ and 3′ ends and alternative promoter usage. Although it originally came...
Autores principales: | Logotheti, Stella, Richter, Christin, Murr, Nico, Spitschak, Alf, Marquardt, Stephan, Pützer, Brigitte M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506118/ https://www.ncbi.nlm.nih.gov/pubmed/34650986 http://dx.doi.org/10.3389/fcell.2021.737735 |
Ejemplares similares
-
Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness
por: Richter, Christin, et al.
Publicado: (2019) -
Neural Networks Recapitulation by Cancer Cells Promotes Disease Progression: A Novel Role of p73 Isoforms in Cancer-Neuronal Crosstalk
por: Logotheti, Stella, et al.
Publicado: (2020) -
A Systems-Based Key Innovation-Driven Approach Infers Co-option of Jaw Developmental Programs During Cancer Progression
por: Marquardt, Stephan, et al.
Publicado: (2021) -
MiRNAs Targeting Double Strand DNA Repair Pathways Lurk in Genomically Unstable Rare Fragile Sites and Determine Cancer Outcomes
por: Marquardt, Stephan, et al.
Publicado: (2020) -
LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1
por: Logotheti, Stella, et al.
Publicado: (2020)